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Risk Mitigation Strategies ​

1. Monitor Hematocrit ​

HCT LevelAction
< 50%Normal — monitor
50–54%Donate blood (therapeutic phlebotomy) if symptomatic
> 54%Reduce T dose or phlebotomy

2. Manage Cardiovascular Risk ​

  • Monitor blood pressure monthly
  • Get annual lipid panels
  • Exercise regularly (150 min/week)
  • Maintain healthy diet
  • Don't smoke

3. Acne Management ​

  • Gentle cleansing twice daily
  • Over-the-counter benzoyl peroxide / salicylic acid
  • See a dermatologist for severe acne

4. Scalp Hair Preservation ​

  • If genetically predisposed to balding, consider finasteride 1 mg/day
  • Minoxidil (Rogaine) for regrowth
  • Accept that some hair loss is normal

5. Regular Monitoring Schedule ​

TestFrequency
Total TEvery 3 months (year 1), then every 6 months
CBC (hematocrit)Every 3 months (year 1), then every 6 months
Lipid panelAnnually
Blood pressureEvery 1–3 months

References ​

  1. UCSF Transgender Care. Masculinising hormone therapy monitoring.